KSR1 and pancreatic ductal adenocarcinoma: Haemotoxylin and eosin staining of the pancreas of Pdx1-Cre;LSL-KrasG12D/+;Trp53flox/flox;Ksr1-/- mice sacrificed at several time points confirmed the presence of pancreatic ductal adenocarcinoma with tumors identified in all mice between 3–4 weeks of age.