Thus, for instance, FOXA1 (Forkhead box protein A1), another member of the forkhead box protein family, was found bound in the exon 3 region of UBE2C gene and, in association with MED1 (mediator complex subunit 1), was capable of altering UBE2C expression levels in prostate cancer cells [29]. Here, MED1 is linked to Familial prostate cancer.