UBE2C and esophageal squamous cell carcinoma: Next, we performed a ChIP assay in the ESCC derived cell line, TE-1, after transfection with both FOXM1 induction expression vector (pcDNA3-FOXM1) and empty control vector (pcDNA3), and it was observed that FOXM1 binds to a described FKHD site (−31 bp) within UBE2C promoter in both conditions.