Our study suggested that OIT was as effective as IIT in HD patients [23,24,25], that the response to OIT could reduce the dose of CERA in HD patients [8,24], and that in the absence of inflammation, low serum levels of ferritin and hepcidin-25 could be predictive of the response to OIT or IIT as reported in non-dialysis CKD [42] and our previous HD patients [25]. The gene discussed is HAMP; the disease is Huntington disease.