Given the striking effect of UMOD deficiency on enhanced KIM‐1 expression after obstruction‐induced kidney, in vitro studies were performed to determine if UMOD can down‐regulate KIM‐1 expression in a human cell line derived from a renal adenocarcinoma that is known to express KIM‐1 (769‐P) (Zhang et al. This evidence concerns the gene UMOD and papillary renal cell carcinoma.