KDM6B and myelodysplastic syndrome: In addition, the expression of KDM6B is significantly elevated in specimen of multiple myeloma (MM) patients, in the bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs) of patients with myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) (Ohguchi et al. 2017; Oppermann 2016; Wei et al. 2016).