LMX1B and nail-patella syndrome: LMX1B, encoding LIM homeobox transcription factor 1β, is required for podocyte differentiation and its mutations typically cause nail-patella syndrome characterized by dystrophic nails, patellar hypoplasia/aplasia with other skeletal abnormalities and SRNS (66), but LMX1B mutations were also reported in patients with non-syndromic SRNS (67).