FOXP3 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome: In mice, the homologous transcription factor Foxp3 (indicated as murine protein by the lower case letters; a consensus followed by most, but not all researchers) exerts the same function and truncated Foxp3 protein resulting from of a 2 bp insertion, that generates a frameshift and premature stop codon, leads to the scurfy phenotype, similar to IPEX syndrome (11).