CCL3 and diabetic neuropathy: The current study has shown that in the lumbar spinal cord of STZ-induced diabetic neuropathic mice, a marker of microglia activation is upregulated in correlation with increased protein levels of CCL3 and CCL9 as measured on day 7, suggesting that these chemokines are very important in the development of diabetic neuropathy and that their source are microglial cells.