CD4 and myeloid sarcoma: By analysis of gene expression patterns (such as RT-PCR and RNA-seq) or epigenomic features [such as chromatin immunoprecipitation sequencing (ChIP-seq) and DNase hypersensitivity sites], all immune cells (including microglia) and neuron cells partly express MS risk genes (16, 53, 54), but MS risk SNPs are preferentially more enriched in the SE region of CD4+ T cells, than in that of B cells and monocytes (32, 33).