Since, both TLR2 and TLR4 expression has been reported to be elevated in the PBMCs from MS patients and soluble forms for both of these receptors (sTLR2 and sTLR4) were detected in various infectious and non-infectious inflammatory conditions, we also measured sTLR4 levels in the serum samples (31, 32). Here, TLR4 is linked to myeloid sarcoma.