CD4 and adult T-cell leukemia/lymphoma: One to ten percent of infected carriers develop a severe HTLV-1-associated disease during their life: Adult-T-cell leukemia/lymphoma (ATLL), a CD4+ T lymphoproliferation of very poor prognosis with a mean survival time of 6 months in the acute form, or a progressive neurological disorder named Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM) (Yamano and Sato, 2012; Bangham et al., 2015).