GH1 and chronic kidney disease: Somatropin is a biological product containing recombinant growth hormone (rGH) that is approved in adults with pronounced GH deficiency as replacement therapy and for a wide range of conditions associated to growth disturbances and short stature in children, such as Turner or Prader–Willi syndrome, GH deficiency, chronic kidney disease (CKD) or in short children/adolescents born small for gestational age (SGA).