This agent could be transformed into reactive toxic metabolites by the CYP450 system to cause liver injury, characterized by the elevation of serum ALT and AST, and morphological changes including hepatocyte inflammation, necrosis and steatosis, etc. (Li et al., 2014; Abdel-Bakky et al., 2015; Liang et al., 2015). The gene discussed is GPT; the disease is steatosis.