However, it was recently reported that schisandrin B and schisandrae fructus oil could elevate hepatic and serum triglyceride levels, heighten serum alanine aminotransferase (ALT) activity, and eventually induce hepatotoxicity (hypertriglyceridemia, hepatomegaly and liver damage) in mice (Zhang et al., 2014). Here, GPT is linked to hypertriglyceridemia.