It was reported that the mRNA expressions of liver CYP450s, including CYP2C11, CYP2E1, CYP3A2, and CYP1A2, were depressed in ALI model rat, indicating the reduction of the protein expression and function of liver CYP450 enzymes (Jia et al., 2007). Here, CYP2E1 is linked to acute respiratory distress syndrome.