The numbers of CD8+ DCs, CD11b+ DCs, and CD11c− CD11b+ myeloid cells in the spleen 24 h after infection were unaffected by Il27ra deletion; however, the number of pDCs at this time was significantly reduced, by approximately 2-fold, in Il27ra−/− mice compared to WT mice (Fig. 3E). This evidence concerns the gene ITGAM and infection.