In a small group of children with JIA-related anterior uveitis, serum interleukin-2R levels were significantly increased,72 while in a larger cohort of children there was a significant correlation between the presence of anterior uveitis and aqueous humour levels of transthyretin.73 Until reliable biomarkers are found, management relies on frequent ophthalmic examination. This evidence concerns the gene TTR and anterior uveitis.