Intriguingly, cyp7a1 overexpression in the liver was associated specifically with buffered liver inflammation (Fig. 8): the number of neutrophils in the liver was increased in the presence of the intestinal tumor (Fig. 4P-R), which was significantly ameliorated by overexpression of cyp7a1 in the liver (Fig. 8E). The gene discussed is CYP7A1; the disease is intestinal neoplasm.