To determine whether this is the case, we treated THP1 AML cells with OG86 or DMSO vehicle for 24 hr and then performed concomitant RNA sequencing (RNA-seq) and chromatin immunoprecipitation with next-generation sequencing (ChIP-seq) using antibodies against histone methylation and acetylation marks, as well as LSD1. Here, KDM1A is linked to acute myeloid leukemia.