3 K. D. K. D. Coon Coon  et al., “ A High‐Density Whole‐Genome Association Study Reveals That APOE Is the Major Susceptibility Gene for Sporadic Late‐Onset Alzheimer's Disease A High‐Density Whole‐Genome Association Study Reveals That APOE Is the Major Susceptibility Gene for Sporadic Late‐Onset Alzheimer's Disease ,”  Journal of Clinical Psychiatry Journal of Clinical Psychiatry 68 68 , no.  4 4  ( 2007 2007 ):  613 613 ‐ 18 18 . The gene discussed is APOE; the disease is Alzheimer disease.