Interestingly, LC3B-positive dots were most prominently seen in keratinocytes of the proximal hair matrix below Auber’s line, the most rapidly proliferating compartment of the HF epithelium [25], and in the precortical hair matrix (Fig 1I and 1II), i.e., the epithelial compartment where undifferentiated HF keratinocytes become committed to undergo terminal differentiation into the cells of the inner root sheath, hair shaft cortex, or medulla and begin synthesizing large quantities of specific hair keratins [26]. Here, MAP1LC3B is linked to hydrops fetalis.