KLK3 and posterior cortical atrophy: The D’Amico or National Comprehensive Cancer Network criteria are frequently used to predict the outcomes of patients with high-risk PCa, which include cT2c or T3a stage, GS at biopsy ≥ 8, and PSA > 20 ng/ml; it is not known if each factor has equivalent weightage in predicting the prognoses in such patients.