CD40LG and coinfection: All positive samples for DENV or ZIKV RT-PCR despite coinfection or presence of CHIKV anti- IgM antibodies; ¥ Serotypes of DENV monoinfection: DENV-1 (45/51 [88.2%]) and DENV-4 (6/51 [11.7%]); $ Serotypes of DENV/ZIKV coinfection: DENV-1 (17/18 [94.4%]) and DENV-4 (1/18 [5.5%]); ω Since we considered only molecular diagnosis for mono and co infections classification, two ZIKV PCR positive patients who also presented dengue NS1 positive test were not include in the analyses as ZIKV monoinfection or DENV/ZIKV coinfection.