A transwell assay showed that the miR-148b-3p inhibitor up-regulated the migration and invasion of SGC-7901NM cells, while the Rac1 inhibitor NSC23766 and Cdc42 inhibitor ML141 could block miR-148b-3p inhibitor-mediated GC migration and invasion (Fig. 7b). The gene discussed is CDC42; the disease is gastric cancer.