HIF1A and neoplasm: It is also interesting to note that the initial time of measurable tumors of IFN-treated cells after inoculation is earlier than those of cells without acute exposure of IFN despite of HIF-1α expression status (e.g. three out of four mice with pSuper + IFN cells and two out of four mice with pSuper cells are with measurable tumor formed at 18th day after inoculation).