Utilizing miCLIP coupled with ribosome profiling, it is elucidated that METTL3 augments m6A levels of its target genes including myelocytomatosis (MYC), B cell lymphoma 2 (BCL2), and phosphatase and tensin homolog (PTEN) genes in the human acute myeloid leukemia (AML) MOLM-13 cell line, thereby promoting the translation of these mRNAs. The gene discussed is BCL2; the disease is acute myeloid leukemia.