It was found there was no difference in amount of RT products between cycling HCT116 p53+/+ and cycling HCT116 p53−/− cells at 16 h post infection, however HIV-1 RT product was decreased about 2.1 times in HCT116 p53+/+ cells compared to HCT116 p53−/− cells in non-cycling cells (Fig. 2a). This evidence concerns the gene TP53 and infection.