Transfection experiments with CedPV P protein demonstrated that the IFN response in HEK293T or HeLa-CCL2 cells was less antagonized when to compared to IFN signaling antagonism with HeV P protein [50] and infection with wild-type CedPV stimulated the IFN-β response in infected HeLa-CCL2 cells [49]. This evidence concerns the gene CCL2 and infection.