Similarly, the rCedPV-wt infected HeLa-USU exhibited extensive syncytial CPE at 72 hpi when EFNB2 was expressed, and this phenotype was not observed with HeLa-USU cells or HeLa-USU-EFNB3, which remained as healthy monolayers at this post-infection time point (Fig. 5b). This evidence concerns the gene EFNB2 and infection.