We observed that FAI, HOMA-IR, TG and OPN, but not PCOS status, explained 33.5% of the variance in LFC (adjusted R2 = 0.335, P < 0.001) with FAI (β = 0.347, P < 0.001), HOMA-IR (β = 0.201, P = 0.013), TG (β = 0.236, P = 0.004) and OPN (β = 0.178, P = 0.023, Table 3) being significant independent contributors. This evidence concerns the gene SPP1 and polycystic ovary syndrome.