CEACAM5 and neoplasm: In univariate analysis, age was associated with prognosis (p = 0.042), and treatment year (p < 0.0001), PS (p < 0.0001), symptoms (p = 0.039), tumor location (p < 0.0001), M category (p < 0.0001), grade of liver metastasis (p < 0.0001), tumor differentiation (p < 0.0001), preoperative CEA levels (p < 0.0001), and primary tumor resection (p < 0.0001) were also significantly associated with OS (Table 2).