PLAT and ischemic stroke: Along with other known risk factors for hemorrhage such as age, renal disease, and stroke volume [7], CMBs may also be associated with hemorrhage risk [8, 9] .The reported prevalence of CMBs on pre-IV tPA imaging ranges from 15 to 40% [10, 11]. This is clinically relevant, as it is becoming increasingly common to perform an MRI as part of the acute work-up of ischemic stroke [12]. In addition, there is increasingly rapid electronic access to patient’s prior MR imaging that may show incidental CMBs.