TCF3 and B-cell acute lymphoblastic leukemia: A novel HL susceptibility locus on chromosome 19p13.3 has been recently identified and includes the transcription factor 3 gene (known as TCF3 or E2A immunoglobulin enhancer-binding factors E12/E47), previously known to be associated with pre-B-cell acute lymphoblastic leukemia (B-ALL) [109].