PLCB4 and mesothelioma: Furthermore, these studies showed that the YAP-dependent transcriptional activations of cyclin D2 (CCND2), forkhead box M1 (FOXM1), and phospholipase C beta 4 (PLCB4) are involved in mesothelioma cell growth [63,64], suggesting that activated YAP influences diverse cellular processes, thereby resulting in mesothelial cell transformation.