NF2 and mesothelioma: However, it was shown that the mutant with a C-terminal deletion of 40 residues was incapable of restoring proper growth inhibition in NF2-null mesothelioma cells [15], and that merlin truncated by 63 residues at the C-terminus did not cause growth arrest of primary Schwann cells [13], indicating the importance of the CTD for the antitumor activity of merlin.