A recent analysis of 20 different cytokines and chemokines (some also included here) in culture supernatants harvested from HNSCC tumor tissue-derived cell suspensions, showed, in accordance with the present study, high tumor related levels of CXCL9, CXCL10, and CCL20 and decreased levels of CCL5 [23]. Here, CCL5 is linked to head and neck squamous cell carcinoma.