GJA5 and atrial fibrillation: (2) Other AF-linked Cx40 missense mutants (G38D, I75F, V85I, A96S, M163V, L221I, L229M) and those in the present study (K107R, L223M, Q236H, and I257L) showed GJ plaques at the cell–cell interfaces [11,14,38,39].