The Ij deactivations of the GJs formed by AF-linked mutants could be fitted by a single exponential process and the τ–Vj plots were not statistically different from those of wildtype Cx40 GJs (filled black circles), except Q236H GJ that showed consistently lower τs at all tested Vjs (Figure 4B, p < 0.05). The gene discussed is GJA5; the disease is atrial fibrillation.