Increased DNA damage response activation in C9orf72-ALS patients has been corroborated by two separate reports (Farg et al., 2017; Walker et al., 2017), which demonstrated that motor neurons from C9orf72-ALS patients display increased levels of ΥH2AX phosphorylation. The gene discussed is C9orf72; the disease is amyotrophic lateral sclerosis.