TGFB1 and intrahepatic cholangiocarcinoma: Moreover, TGF-β1 expression was associated with portal vein invasion (p = 0.022), intrahepatic metastasis (p = 0.049), and OS rate (p = 0.0062), but was not associated with lymph node metastasis (p = 0.31) in patients with ICC (Supplemental Table S2, Figure 5).