A combined OR of 1.25 for trigger PSA predicting recurrence from choline PET/CT positive findings with biochemical failure prostate cancer after initial treatment was found in our meta-analysis, after a subgroup analysis, the combined OR were 2.21 and 1.45 in 18F-choline and C11-choline PET/CT, respectively. Here, KLK3 is linked to prostate carcinoma.