AGTR1 and breast carcinoma: Although patients with the AGTR1 A1166C A allele exhibit higher miR-155 and AGTR1 levels than those with the C allele [13], and this polymorphism is associated with coronary artery disease [14] and breast cancer [15], current evidence does not support an association between AGTR1 A1166C and CKD in East Asians.