Expression ofcell-division cycle protein 20 (CDC20), isoleucine glutamine motif-containingGTAase-activating proteins (IQGAP3), DNA topoisomerase 2-alpha (TOP2A), andubiquitin-conjugating enzyme E2 C (UBE2C) in BC tissue samples from BC patients wassignificantly higher than that in tissue samples from controls(P=0.011, P<0.001,P<0.001, and P=0.003, respectively)(Table 2 and Figure 2). Here, TOP2A is linked to breast cancer.