IFNB1 and nasopharyngeal carcinoma: As the biological effects of IFNβ in NPC cells can be obtained at concentrations which are achieved in the serum of patients treated with IFNβ [24, 32], it might very well be that the induction of apoptosis in NPC cells via the TRAIL-signaling pathway could at least contribute to the therapeutic effect of IFNβ observed in patients with NPC.