The following 18 genes used in our M2EFM models appear in the Cancer Gene Census: AFF3, BCL11A, CD79A, CD79B, EGFR, ERBB4, ESR1, FOXA1, GATA3, IRF4, ITK, LCK, MYB, POU2AF1, PRF1, PTPRC, RET, TNFRSF17. The gene discussed is ITK; the disease is cancer.