In our previous genetic association study, we found that variation in two endoglin tSNPs (rs11792480, rs10121110) was associated with susceptibility to/protection from preeclampsia in an American Caucasian cohort, while variation in a TGFβR2 tSNP (rs6550005) was associated with preeclampsia in both an American Caucasian and an African American cohort. This evidence concerns the gene ENG and preeclampsia.