Six intronic tSNPs in two ENG pathway candidate genes were found to be significantly associated with preeclampsia status in the Norwegian cohort, TGFβR1(rs6478974) and TFFβR2(rs11129420, rs6802220, rs1155708, rs3773640, rs3773663) (Table 4) (Refer to Supplemental Materials for tSNP/SNP genotype distributions). This evidence concerns the gene TGFBR1 and preeclampsia.