In this study we predicted the miRNAs that target NMT1/NMT2/MetAP2 transcripts, and the possibility of these interactions to inhibit NMT1/2 expression, and their function in relation to cancer, stem cell, T-cell/B-cell signaling and infectious diseases, using the bioinformatics techniques TargetScan 7 and DIANA. This evidence concerns the gene METAP2 and cancer.