The NMT1/2 and MetAP2 genes’ targeting miR-132-5p was found to be associated with fungal infection of human dendritic cells with Candida albicans and Aspergillus fumigatus and regulates immune responses through the interactions with FKBP1B, KLF4, and SPN genes. The gene discussed is KLF4; the disease is fungal infectious disease.