Although the levels of hVEGF are similar in both tumour models, mVEGF is significantly increased in the serum of mice bearing MCF-7 (Fig. 4d; 86.2 ± 10.6 MCF-7 vs. 15.7 ± 6.2 MDA-MB-231), pointing to the stromal compartment as the main source of VEGF in MCF-7 model. Here, VEGFA is linked to neoplasm.