Such dense clusters of hypermethylation included the translocated ABL1 promoter, the promoter regions of Wilms tumor 1 (WT1), a transcription factor overexpressed in myeloid malignancies (Rosenfeld et al., 2003), and the promoter of the ZNF577 gene that encodes a zinc finger protein (Figs 2C,D, S4A). Here, ABL1 is linked to myeloid neoplasm.