miR‐146a has been shown to be a circulating miRNA that is increased in synovial tissues and fibroblasts in rheumatoid arthritis (RA) patients as a particularly important negative regulator of nuclear factor‐κB (NF‐κB) signaling (Murata et al., 2010; Stanczyk et al., 2008; Taganov, Boldin, Chang & Baltimore, 2006). The gene discussed is NFKB1; the disease is rheumatoid arthritis.