The result of the metoprolol‐paroxetine/fluoxetine and metoprolol‐citalopram comparison is in line with a case control study performed by Kurdyak PA et al.7 They reported that compared with the combination of non‐inhibiting CYP2D6 antidepressants‐metoprolol, there was no significant association of metoprolol‐paroxetine/fluoxetine with the risk of bradycardia in elderly. Here, CYP2D6 is linked to Bradycardia.