AFP and hepatocellular carcinoma: ROC analysis results showed that the AUC and 95% confidence interval (CI) of miR‐122, miR‐148a, and miR‐1246 was 0.816 [95% CI: 0.720–0.889, P < 0.0001), 0.891 (95% CI: 0.809–0.947, P < 0.0001), and 0.785 (95% CI: 0.686–0.865, P < 0.0001), respectively, in discriminating HCC from LC, and only miR‐148a was significantly higher than AFP 0.712 (95% CI: 0.607–0.803, P < 0.0001) (Fig. 4A–D).