Specifically, there was no significant association between PD‐L1 expression with mixed histology (95% CI: 0.89–5.14, P = 0.089) and squamous NSCLC (95% CI: 0.97–2.87, P = 0.066) with no heterogeneity (I2 = 0, P = 0.369; I2 = 0, P = 0.889; Fig. 3). Here, CD274 is linked to non-small cell lung carcinoma.