As manipulating 5ht2c gene might have skewed the interpretation of observed effect (indeed, the studies attributed distinct roles to SNORD115 with regards to post-transcriptional processing of 5ht2c), we monitored alternative splicing and A-to-I editing profiles of endogenously expressed serotonin receptor 2c transcript throughout retinoic acid-induced neuronal differentiation of murine embryonic carcinoma cell line P19 that concomitantly expresses SNORD115. Here, SNORD115 is linked to embryonal carcinoma.