Out of 9 inflammatory cytokines analyzed, six-cytokines including IL-4 (p = 0.0317), IL-10 (p = 0.0159), IL-13 (p = 0.0317), IFN-γ (p = 0.0286), GM-CSF (p = 0.0357) and TNF-α (p = 0.0357) were found to be significantly increased, whereas IL-2, IL-5 and IL-12 did not show significant difference in DM when compared with control subjects (Table 2). The gene discussed is TNF; the disease is diabetes mellitus.